Cihan University-Erbil Scientific Journal

Age of women as a parameter Affecting CA-125, TSH and CBC

2023-02-06T06:38:30+00:00

One of the Cancer’s antigens is the CA125, which is a protein antigen, found at excessively high levels in females characterized with ovarian cancer. It is suggested for ovarian cancer screening of women that are at higher risk to get the disease, despite its limited sensitivity and specificity. This study is conducted to identify possible correlations between CA125 and TSH levels with parameters of hematological origin among women of different ages. This study included 44 healthy looking females. Most but not all patients were from Erbil. The study revealed that, CA125 and TSH levels were not associated. Also, the elevation of the CA125 levels in the females could be related to other non-cancerous factors such as menstrual cycle, or postmenopausal. Also WBC parameters and Hb levels were not affected by CA125. The only parameter that was affected by CA125 elevation was RBCs. The research recorded a significant difference of RBC between patient group and control group. Also recorded, no difference to be considered as an indication related to the difference in women age.

Full-Smart Intermittent Water Supply Monitoring, Managing, and Distributing System Based on IoT

2023-02-06T06:43:24+00:00

Water supply scarcity has become a serious problem for many countries and cities, especially in the last few years when there has been less rain in many areas. So, managing, monitoring, and distributing the water supply and consumption of the people has become an urgent task for many local and national governments. Monitoring how the water is used by the population in different regions helps a lot in the more efficient management of the water supply, thus helping in solving the water scarcity problem. The proposed system includes continuous water level monitoring of wells and storage reservoirs in the city, as well as continuous monitoring of the daily water consumption needs of each household in each neighborhood based on a group of criteria such as the number of residents, the area of green space, and the temperature of the air. This is followed by a fair amount of water being automatically distributed at regular periods to each consumer based on the estimated total amount of water. This is done through smart water meters, remote actuation of valves, and remote water pumps based on IoT devices, which are all under the supervision of a web-based system. Moreover, an application has been developed for use by consumers so that they can monitor their water consumption, be informed about the next water distribution time and the amount of predicted water, check the water meter status, check the air in water pipes, and water bill inquiry and payment.

Architecture Students Self-Report Wellbeing Assessment Based On Quality Learning Environment in Design Studio

2023-02-28T07:54:47+00:00

Higher education students’ difficulties, especially students in architecture education lead students to health problems. The design studio is the heart of architecture education and students spent most of their time with staff. Students tend to do various activities in the studio such as demonstrating, model-making, drawing, and lecturing. Therefore, the learning environment in the studio should attract students to spend most of their time in the studio happily. This research focused on a mixed method to assess the relationship between students’ wellbeing and the quality learning environment in the design studio. The students’ self-report assessment for the wellbeing situation has been used that depends on students experience in the design studio. For this reason, architecture design studios at private universities in Erbil city have been selected as a case study. The statistical program SPSS has been used to test hypotheses and analyze data. The findings of this study represent the significant positive relationship between students’ wellbeing and the quality learning environment in the design studio. Furthermore, the study illustrates the significance of the quality learning environment in the design studio and its role in the development of the student’s wellbeing.

Inhibition of Rac 1 Protect Against Platelet Induced Liver and Kidney ‎Injury in Diabetes Mellitus

2023-02-28T08:53:02+00:00

Diabetes mellitus both (Type 1 and Type 2) are one of the common causes for activation of platelet. Inflammation-induced abnormal platelet function contributes to chronic complications, which are the leading causes of death and morbidity among diabetics. Rac1 has been shown to regulate a variety of platelet functions; predicted Rac1could regulate platelet release of CXCL4, which leads to kidney injury in Diabetes Mellitus. Diabetes mellitus' effect on Rac1 activation, a 21kD G-protein implicated in platelet activation, was investigated and platelet induced inflammation and kidney injury. Swiss albino male mice were pretreated with 5 mg/kg of a specific Rac1 inhibitor NSC23766 and injected with (45 mg/kg body wt.) streptozotocin, twice for five days. Moreover, the concentration of serum chemokines CXCL4 were assayed using ELISA and histology score for kidney were examined. Our results showed that Diabetes mellitus was induced in mice by streptozotocin. In addition, platelet chemokines (CXCL4) were markedly higher in diabetic mice when compared to the sham (control) group. Moreover, pretreatment with NSC23766 decreased liver and kidney injury assessed by histology score, P-value <0.05. Our study reveals that Rac1 has a critical role in platelet chemokines secretion due to diabetes-induced inflammation in the liver and kidneys, targeting Rac1 could be a target for innovative treatment to control inflammation in diabetic individual. Targeting platelets involved in inflammatory pathways could be part of a strategy in order to control and manage diabetes and its consequences.

Assessment of Minor Disorders among Pregnant Women Attending Malafandi Primary Health Care Centre/Erbil-City

2023-04-30T10:09:46+00:00

Minor disorder are the discomforts as associated with the pregnancy such as nausea, vomiting, backache, heart burn, constipation, varicose vein, haemorrhoids, frequency of urination, fatigue, and leg cramps. Many women experience some minor disorder during pregnancy; these discomforts should be adequately as they may occur due to hormonal changes and postural changes. The aim of this study was to assess the minor disorder among pregnant women. A descriptive study was conducted in Malafandi Primary Health Care Centre, in December 2020 to January 2021, one hundred pregnant were taken and the data were collected by direct interview. The highest percentage of them within age group between 25–34 years old, graduated from high school with middle economic status. All of them had minor disorders as nausea and vomiting, backache, heart burn, leg cramps, varicose vein, haemorrhoids, fatigue, frequency of urination, constipation, and loss of appetite. There is a statistical significant association between age group with nausea and vomiting, and haemorrhoids (P- value ≤ 0.001 and 0.002 respectively). The findings of this study indicated that most common minor disorder in pregnancy came from fatigue while the lowest came from constipation.

The Protective Rolls of Taraxacum officinale against Carbone Tetrachloride Infarction in the Liver

2023-05-20T13:30:09+00:00

Carbon tetrachloride (CCl4) is a liquid that is colorless, transparent, inflammable, and volatile. Its central carbon atom is surrounded by four Cl- atoms. As a result, the objective of this effort was to estimate the anti-oxidant properties of silver nanoparticles (AgNPs) made utilizing aqueous plant extracts from Taraxacum officinale leaves. A green synthesis of AgNPs using a synergistic aqueous extract from T. officinale leaves was tested against liver damage in rats caused by CCl4. The rats were randomly distributed into seven groups: Group 1: Control group, Group 2: Olive oil group, Group 3: AgNPs-treated group (100 mg/kg BW.), Group 4: AgNPs-treated group (200 mg/kg BW.), Group 5: CCl4 + Olive oil group, Group 6: (CCl4 + Olive Oil) + 100 mg/kg of AgNPs-treated group, and Group 7: (CCl4 + Olive oil) + 200 mg/kg of AgNPs-treated group one a week for 6 weeks. This study demonstrated a sustainable method for synthesizing AgNPs utilizing T. officinale leaf (TOL) extract. To characterize the synthesized T. officinale leaf-silver nanoparticles (TOL-AgNPs), various microscopic and spectroscopic methods were used. The effectiveness of the biosynthesized TOL-AgNPs against CCl4 was tested to assess their antioxidant potential. The antioxidant properties of synthetic TOL-AgNPs were also evaluated. Histopathological research showed that all groups treated with nano-extract had less severe inflammatory responses. Our findings demonstrated that AgNPs synthesized using the leaves of T. officinale possess a potential anti-oxidant activity against CCl4-induced liver injury in rats.

The Effect of Hypericum perforatum Extract on Gastric Ulcer Development in Rat Models

2023-05-20T13:32:15+00:00

Gastric ulcer is a serious condition that results from the wearing/tearing of the stomach mucosa. A physiological equilibrium is maintained between mucosal defense and aggressive factors. In this study, the effectiveness of medicinal plants (Hypericum perforatum) in the management of gastric ulcer was compared to that of omeprazole, a well-known drug for gastric ulcer. This study involved numerous study groups of male rats comprising of the following: the first group (control group exposed to H. pylori and fed with normal animal feed), the second group (rats exposed to H. pylori and treated with two doses {of 250 mg/kg and 500 mg/kg} of aqueous H. perforatum), and the third group (rats exposed to H. pylori and treated with 20 mg/kg of omeprazole). The outcome of the study demonstrated that a high dose of H. perforatum prevents (50.65%) the development of stomach ulcers. The group treated with omeprazole revealed a formation of stomach ulcers (24.50%). A high dose of the aqueous plant extracts showed greater effectiveness in preventing gastric ulcer formation compared to the lower dosage.