Cihan University-Erbil Scientific Journal

Age of women as a parameter Affecting CA-125, TSH and CBC

Muhsin H. Ubeid — 2023-01-30

One of the Cancer’s antigens is the CA125, which is a protein antigen, found at excessively high levels in females characterized with ovarian cancer. It is suggested for ovarian cancer screening of women that are at higher risk to get the disease, despite its limited sensitivity and specificity. This study is conducted to identify possible correlations between CA125 and TSH levels with parameters of hematological origin among women of different ages. This study included 44 healthy looking females. Most but not all patients were from Erbil. The study revealed that, CA125 and TSH levels were not associated. Also, the elevation of the CA125 levels in the females could be related to other non-cancerous factors such as menstrual cycle, or postmenopausal. Also WBC parameters and Hb levels were not affected by CA125. The only parameter that was affected by CA125 elevation was RBCs. The research recorded a significant difference of RBC between patient group and control group. Also recorded, no difference to be considered as an indication related to the difference in women age.

Full-Smart Intermittent Water Supply Monitoring, Managing, and Distributing System Based on IoT

Mohammed M. Ahmed — 2023-01-30

Water supply scarcity has become a serious problem for many countries and cities, especially in the last few years when there has been less rain in many areas. So, managing, monitoring, and distributing the water supply and consumption of the people has become an urgent task for many local and national governments. Monitoring how the water is used by the population in different regions helps a lot in the more efficient management of the water supply, thus helping in solving the water scarcity problem. The proposed system includes continuous water level monitoring of wells and storage reservoirs in the city, as well as continuous monitoring of the daily water consumption needs of each household in each neighborhood based on a group of criteria such as the number of residents, the area of green space, and the temperature of the air. This is followed by a fair amount of water being automatically distributed at regular periods to each consumer based on the estimated total amount of water. This is done through smart water meters, remote actuation of valves, and remote water pumps based on IoT devices, which are all under the supervision of a web-based system. Moreover, an application has been developed for use by consumers so that they can monitor their water consumption, be informed about the next water distribution time and the amount of predicted water, check the water meter status, check the air in water pipes, and water bill inquiry and payment.

Architecture Students Self-Report Wellbeing Assessment Based On Quality Learning Environment in Design Studio

Ashti Y. Hussein — 2023-03-01

Higher education students’ difficulties, especially students in architecture education lead students to health problems. The design studio is the heart of architecture education and students spent most of their time with staff. Students tend to do various activities in the studio such as demonstrating, model-making, drawing, and lecturing. Therefore, the learning environment in the studio should attract students to spend most of their time in the studio happily. This research focused on a mixed method to assess the relationship between students’ wellbeing and the quality learning environment in the design studio. The students’ self-report assessment for the wellbeing situation has been used that depends on students experience in the design studio. For this reason, architecture design studios at private universities in Erbil city have been selected as a case study. The statistical program SPSS has been used to test hypotheses and analyze data. The findings of this study represent the significant positive relationship between students’ wellbeing and the quality learning environment in the design studio. Furthermore, the study illustrates the significance of the quality learning environment in the design studio and its role in the development of the student’s wellbeing.

Inhibition of Rac 1 Protect Against Platelet Induced Liver and Kidney ‎Injury in Diabetes Mellitus

Rundk A. Hwaiz — 2023-03-01

Diabetes mellitus both (Type 1 and Type 2) are one of the common causes for activation of platelet. Inflammation-induced abnormal platelet function contributes to chronic complications, which are the leading causes of death and morbidity among diabetics. Rac1 has been shown to regulate a variety of platelet functions; predicted Rac1could regulate platelet release of CXCL4, which leads to kidney injury in Diabetes Mellitus. Diabetes mellitus' effect on Rac1 activation, a 21kD G-protein implicated in platelet activation, was investigated and platelet induced inflammation and kidney injury. Swiss albino male mice were pretreated with 5 mg/kg of a specific Rac1 inhibitor NSC23766 and injected with (45 mg/kg body wt.) streptozotocin, twice for five days. Moreover, the concentration of serum chemokines CXCL4 were assayed using ELISA and histology score for kidney were examined. Our results showed that Diabetes mellitus was induced in mice by streptozotocin. In addition, platelet chemokines (CXCL4) were markedly higher in diabetic mice when compared to the sham (control) group. Moreover, pretreatment with NSC23766 decreased liver and kidney injury assessed by histology score, P-value <0.05. Our study reveals that Rac1 has a critical role in platelet chemokines secretion due to diabetes-induced inflammation in the liver and kidneys, targeting Rac1 could be a target for innovative treatment to control inflammation in diabetic individual. Targeting platelets involved in inflammatory pathways could be part of a strategy in order to control and manage diabetes and its consequences.