Serum Fibroblast Growth Factors 23, Chemerin, and Vitamin D Levels in Patients with Psoriasis

Keywords: Serum fibroblast, psoriasis, fibroblast growth factor 23, chemerin, 1,25 (OH)2D


The aim of the study was to compare the levels of fibroblast growth factor 23 (FGF23) and chemerin, as well as Vitamin D in psoriasis sufferers and healthy controls. From 2021 to 2022, ninety subjects were studied. The study comprised 45 individuals with psoriasis and 45 healthy controls. Serum fasting FGF23 and chemerin levels of the study group were examined by sandwich enzyme-linked immunosorbent assay. The results demonstrate that the mean serum FGF23 and chemerin quantities in psoriasis patients were greater than in controls, with a statistically significant. Patients with psoriasis, on the other hand, had considerably lower blood Vitamin D levels than healthy controls. These findings demonstrate that psoriatic patients have lower Vitamin D levels than healthy controls, and they add to the growing body of data linking FGF23, chemerin Vitamin D levels, and the course of psoriasis.


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Author Biographies

Shatha N. Tawfeeq, Department of Medical Microbiology, Cihan University-Erbil, Kurdistan Region, Iraq

Shatha N. Tawfeeq is an Assistant Lecturer at the Department of Medical Microbiology, College of Science, Cihan University. She got the B.Sc. degree in General Biology, the M.Sc. degree in Zoology. Her research interests are in Physiology, Endocrinology and Hematology.

Moayad M. Al Anzy, Department of Pharmaceutical Sciences, Tikrit University, Tikrit, Iraq

Moayad M. Al Anzy an Assistant Prof. at the Department of Clinical Science Laboratory, College of Pharmacy, Tikrit University. He got the B.Sc degree in in Veterinary Medicine and Surgery, the M.Sc degree in Clinical Biochemistry, the Ph.D degree in Clinical Biochemistry

Entedhar R. Sarhat, Department of Basic Science, Faculty of Medicine, Tikrit University, Tikrit, Iraq

Entedharr R. Sarhat is a Professor at the Department of Basic Science, College of Dentistry, Tikrit University. She got the B.Sc degree in Veterinary Medicine and Surgery, the M.Sc degree in Biochemistry, the Ph.D degree in Biochemistry. Dr. Entedharr is a member of Expert Committee in Iraqi Ministry of Higher Research and Scientific Research


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How to Cite
Tawfeeq S, Al Anzy M, Sarhat E. Serum Fibroblast Growth Factors 23, Chemerin, and Vitamin D Levels in Patients with Psoriasis. cuesj [Internet]. 20Aug.2022 [cited 1Oct.2022];6(2):57-1. Available from:
Research Article