Knowledge and Awareness Towards Food Drug Interaction Among Pharmacists in Erbil City

Behnaz Shahrokhisahneh; Noor O. Mahmoud; Rangin Najmadin; Ala H. Abdulwahab; Sima S. Hamasalh

doi:10.24086/cuesj.v8n2y2024.pp19-25

Behnaz Shahrokhisahneh Department of Nutrition and Dietetics, College of Health Technology, Cihan University-Erbil, Kurdistan Region,Iraq https://orcid.org/0000-0001-5206-7045
Noor O. Mahmoud Department of Nutrition and Dietetics, College of Health Technology, Cihan University-Erbil, Kurdistan Region, Iraq
Rangin Najmadin Department of Nutrition and Dietetics, College of Health Technology, Cihan University-Erbil, Kurdistan Region, Iraq
Ala H. Abdulwahab Department of Nutrition and Dietetics, College of Health Technology, Cihan University-Erbil, Kurdistan Region, Iraq
Sima S. Hamasalh Department of Nutrition and Dietetics, College of Health Technology, Cihan University-Erbil, Kurdistan Region, Iraq

DOI: https://doi.org/10.24086/cuesj.v8n2y2024.pp19-25

Keywords: Erbil, Food-drug interactions, Knowledge assessment, Patient care, Pharmaceutical education

Abstract

In the evolving landscape of healthcare, understanding the potential interactions between pharmaceutical drugs and food is imperative yet often overlooked. This study aimed to assess pharmacists' knowledge of food-drug interactions (FDI) in Erbil city, focusing on comprehension, risk factors, counseling practices, and familiarity with drug databases. Conducted through a survey-based approach, the research involved 100 pharmacists from varying educational backgrounds, sampled purposively from Doctors Street in Erbil. Data collection occurred over two months via a self-administered questionnaire comprising 34 questions covering basic FDI awareness and advanced topics. Results indicate a correlation between higher education levels and a deeper understanding of FDI, particularly in recognizing specific drug-nutrient interactions. Nonetheless, knowledge gaps persist, underscoring the complexity of FDI comprehension. Intriguingly, pharmacists with institute certificates exhibited nuanced understanding in certain scenarios, challenging assumptions about the linear relationship between education and awareness. The study emphasizes the necessity for targeted interventions in pharmaceutical education to address these nuances effectively. These findings contribute to the growing body of knowledge on FDI awareness among pharmacists, highlighting the importance of continuous education to ensure optimal patient care, treatment efficacy, and safety.

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Author Biographies

Behnaz Shahrokhisahneh, Department of Nutrition and Dietetics, College of Health Technology, Cihan University-Erbil, Kurdistan Region,Iraq

Behnaz Shahrokhisahneh is a Lecturer at Cihan University-Erbil in Iraq, specializing in Nutrition and Dietetics. With a Ph.D. in Food Science and Nutrition, she teaches various courses and conducts research in areas such as clinical nutrition, public health, and obesity. She also provides nutritional guidance to athletes and has developed meal replacements for weight reduction

Noor O. Mahmoud, Department of Nutrition and Dietetics, College of Health Technology, Cihan University-Erbil, Kurdistan Region, Iraq

Noor Osama Ahmed Mahmoud is a student who just graduated from department of Nutrition and Dietetics, Cihan University-Erbil, Iraq.

Rangin Najmadin, Department of Nutrition and Dietetics, College of Health Technology, Cihan University-Erbil, Kurdistan Region, Iraq

Rangin Najmadin just graduated from department of Nutrition and Dietetics, Cihan University-Erbil. She is working as coordinator in department of Community Health Nursing in Cihan University-Erbil.

Ala H. Abdulwahab, Department of Nutrition and Dietetics, College of Health Technology, Cihan University-Erbil, Kurdistan Region, Iraq

Ala Husameddin Abdulwahab just graduated from department of Nutrition and Dietetics, Cihan University-Erbil. She is working as coordinator in Cihan University-Erbil.

Sima S. Hamasalh, Department of Nutrition and Dietetics, College of Health Technology, Cihan University-Erbil, Kurdistan Region, Iraq

Sima Sadiq just graduated from Department of Nutrition and Dietetics, College of Health Technology, Cihan University-Erbil, Kurdistan Region, Iraq

References

S. Otles and A. Senturk. Food and drug interactions: A general review. Acta Scientiarum Polonorum, Technologia Alimentaria, vol. 13, no. 1, pp. 89-102, 2014.

M. A. Elgadir. Food-drug interaction and their clinical implications: Selected investigations. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 11, pp. 1-5, 2019.

S. S. Samajdar, S. Mukherjee and S. K. Tripathi. Antimicrobial drug administration and food timings: Clinico- harmacological considerations. Exploratory Animal and Medical Research, vol. 11, no. 1, p. 10, 2021.

V. Pilla Reddy, H. Jo and S. Neuhoff. Food constituent- and herbdrug interactions in oncology: Influence of quantitative modelling on drug labelling. British Journal of Clinical Pharmacology, vol. 87, no. 10, pp. 3988-4000, 2021.

E. S. Sultan, F. A. El-Sahn, E. M. Fetohy and D. T. Mohamed. Knowledge, attitude and practice of physicians and pharmacists working in Alexandria governmental hospitals regarding food drug and drug nutrient interactions. Journal of High Institute of Public Health, vol. 51, no. 3, pp. 121-127, 2021.

N. Bajj, D. Sweidan, M. R. Awies, J. Barakat and H. Al-Sayyed. Awareness of Food-Drug Interactions (FDIs) among Jordanian Dietitians. In: ACM International Conference Proceeding Series, 2021.

C. C. Diaconu, M. A. Cozma, E. C. Dobrică, G. Gheorghe, A. Jichitu, V. A. Ionescu, A. C. Nicolae, C. M. Drăgoi and M. A. Găman. Polypharmacy in the management of arterial hypertension-friend or foe? Medicina (Kaunas), vol. 57, no. 12, p. 1288, 2021.

Y. Yang, Z. Zhang, S. Li, X. Ye, X. Li and K. He. Synergy effects of herb extracts: Pharmacokinetics and pharmacodynamic basis. Fitoterapia, vol. 92, pp. 133-147, 2014.

P. Fagiolino, M. Vázquez, M. Ibarra, C. Maldonado and R. Eiraldi. Drug-drug and food-drug interactions of pharmacokinetic nature. In: ADME Processes in Pharmaceutical Sciences. Springer, Cham. 2018.

O. F. Ajeigbe, A. O. Ademosun and G. Oboh. Relieving the tension in hypertension: Food-drug interactions and anti-hypertensive mechanisms of food bioactive compounds. Journal of Food Biochemistry, vol. 45, no. 3, p. e13317, 2021.

I. Kose, G. Gencyurek, Z. A. Atan and B. O. Elmas. Analysis of drug-food interactions in inpatient treatment: A university hospital case. Medical Research Archives, vol. 9, no. 2, p. 2-11, 2021.

S. I. Oyeleye, O. R. Ojo and G. Oboh. Moringa oleifera leaf and seed inclusive diets influenced the restoration of biochemicals associated with erectile dysfunction in the penile tissue of STZinduced diabetic male rats treated with/without Acarbose drug. Journal of Food Biochemistry, vol. 45, no. 3, p. e13323, 2021.

S. F. Zaidi, R. Mgarry, A. Alsanea, S. K. Almutairi, Y. Alsinnari, S. Alsobaei and K. Ahmed. A questionnaire-based survey to assess the level of knowledge and awareness about drug-food interactions among general public in Western Saudi Arabia. Pharmacy (Basel), vol. 9, no. 2, p. 76, 2021.

A. Y. Abuhelwa, D. B. Williams, R. N. Upton and D. J. R. Foster. Food, gastrointestinal pH, and models of oral drug absorption. European Journal of Pharmaceutics and Biopharmaceutics, vol. 112, pp. 234-248, 2017.

O. Lootens, A. Vermeulen, S. Croubels, S. De Saeger, J. Van Bocxlaer and M. De Boevre. Possible mechanisms of the interplay between drugs and mycotoxins-is there a possible impact? Toxins (Basel), vol. 14, no. 12, p. 873, 2022.

L. Cheng and H. Wong. Food effects on oral drug absorption: Application of physiologically-based pharmacokinetic modeling as a predictive tool. Pharmaceutics, vol. 12, no. 7, p. 672, 2020.

Á. López Mármol, P. L. Fischer, A. Wahl, D. Schwöbel, V. Lenz, K. Sauer and M. Koziolek. Application of tiny-TIM as a mechanistic tool to investigate the in vitro performance of different itraconazole formulations under physiologically relevant conditions. European Journal of Pharmaceutical Sciences, vol. 173, p. 106165, 2022.

M. M. Rahman, S. M. Vadrev, A. Magana-Mora, J. Levman and O. Soufan. A novel graph mining approach to predict and evaluate food-drug interactions. Scientific Reports, vol. 12, no. 1, p. 1061, 2022.

W. S. Snr, A. Bashatah and M. B. A. Al-Rawi. Evaluation of knowledge of food-drug and alcohol-drug interactions among undergraduate students at King Saud University - An observational study. Journal of Multidisciplinary Healthcare, vol. 15, pp. 2623-2633, 2022.

J. M. Benni, M. K. Jayanthi, R. Basavaraj and M. Renuka. Knowledge and awareness of food and drug interactions (FDI): A survey among health care professionals. International Journal of Pharmacology and Clinical Sciences, vol. 1, no. 4, pp. 97-105, 2012.

C. Palleria, A. Di Paolo, C. Giofrè, C. Caglioti, G. Leuzzi, A. Siniscalchi, G. De Sarro and L. Gallelli. Pharmacokinetic drugdrug interaction and their implication in clinical management. Journal of Research in Medical Sciences, vol. 18, no. 7, pp. 601- 610, 2013.

S. P. Borse, D. P. Singh and M. Nivsarkar. Understanding the relevance of herb-drug interaction studies with special focus on interplays: A prerequisite for integrative medicine. Porto Biomedical Journal, vol. 4, no. 2, p. e15, 2019.

N. Makkaoui, A. Halaoui, Z. Atoui, H. Siblini, S. Habib, H. Awada and N. K. Zgheib. Knowledge, attitudes, and practices regarding drug interactions among community pharmacists. Journal of Public Health, vol. 29, no. 6, pp. 1357-1363, 2021.

R. G. Abdulwahid and H. M. Ahmed. Nutritional characteristics of pregnant women and its relation with anemia during pregnancy in a sample of Kurdish women/Iraq. Cihan University-Erbil Scientific Journal, vol. 4, no. 1, pp. 37-44, 2020.

M. Y. Rashid, A. L. Abdulraheem, G. S. Hama Amin, S. S. Weli, R. K. Faraj, A. J. Muhialdin and S. A. Raheem. Prevalence of anemia, iron deficiency anemia and its socio-demographic factors among pregnant women in Garmian province, Kurdistan region of Iraq. Cihan University-Erbil Scientific Journal, vol. 7, no. 1, pp. 60-66, 2023.