Prevalence of AntiHelicobacter pylori Antibodies among Students of Cihan University, Erbil

  • Sarah Hoshyar Maroof Department of Biology, Cihan University-Erbil, Kurdistan Region, Iraq
  • Hadi Mahdi Alsakee Department of Biology, Cihan University-Erbil, Kurdistan Region, Iraq http://orcid.org/0000-0002-3387-8106
  • Gulistan Hussein Muhammad Department of Biology, Cihan University-Erbil, Kurdistan Region, Iraq
  • Asia Sherzad Muhammad Department of Biology, Cihan University-Erbil, Kurdistan Region, Iraq
  • Ilaf Abdulrazaq Rashid Department of Biology, Cihan University-Erbil, Kurdistan Region, Iraq
  • Naza khan Tofiq Sdiq Department of Biology, Cihan University-Erbil, Kurdistan Region, Iraq
Keywords: Anti-H, pylori antibodies, Helicobacter pylori, immunochromatography assay, prevalence

Abstract

Helicobacter pylori is resident in human stomach and causes chronic disease (peptic ulcer and gastritis). The mouth and colon were both known to host a large number of microbes. This study was carried out to investigate the seroprevalence of H. pylori infection among Cihan University students. A total of 197 blood samples were collected from the students (53 females and 144 males) from 13 departments of Cihan University, Erbil, and tested for anti-H. pylori antibodies, using rapid immunochromatography assay. Among 197 students tested, 44 (22.3%) showed positive reaction for H. pylori, 32 males and 12 females. It was non-significantly higher among students with ages ranged between 29 and 32 years old. Twenty-one of infected students were using tap water for drinking. Twenty-six (59.1%) of positive students experienced no symptoms and 18 (40.9%) were symptomatic (13.63% epigastric pain and 27.2% abdominal pain).

Downloads

Download data is not yet available.

References

M. Amieva and R. M. Jr. Peek. “Pathobiology of Helicobacter pylori induced gastric cancer manuel”. Gastroenterology, vol. 150. no. 1, pp. 64-78, 2017.

M. J. Blaser. “Who are we? Indigenous microbes and the ecology of human diseases”. EMBO Reports, vol. 7, no. 10, pp. 956-960, 2006.

L. Fuccio, R. M. Zagari, L. H. Eusebi, L. Laterza, V. Cennamo, L. Ceroni, D. Grilli and F. Bazzoli. “Meta-analysis: Can Helicobacter pylori eradication treatment reduce the risk for gastric cancer?” Annals of Internal Medicine, vol. 151, no. 2, pp. 121-128, 2009.

H. M. Malaty. “Epidemiology of Helicobacter pylori infection”. Best practice & research. Clinical gastroenterology, vol. 21, no. 2, pp. 205-214, 2007.

F. Mégraud. “H pylori antibiotic resistance: Prevalence, importance, and advances in testing”. Gut, vol. 53, no. 9, pp. 1374-1384, 2004.

P. Malfertheiner, F. Megraud, C. O’Morain, F. Bazzoli, E. El-Omar, D. Graham, R. Hunt, T. Rokkas, N. Vakil and E. J. Kuipers. “Current concepts in the management of Helicobacter pylori infection: The maastricht III consensus report”. Gut, vol. 56, no. 6, pp. 772-781, 2007.

L. M. Brown. “Helicobacter pylori: Epidemiology and routes of transmission”. Epidemiologic Reviews, vol. 22, no. 2, pp. 283-297, 2000.

A. Tonkic, M. Tonkic, P. Lehours and F. Megraud. “Epidemiology and diagnosis of Helicobacter pylori infection”. Helicobacter, vol. 17, no. 1, pp. 1-8, 2012.

M. I. Pereira and J. A. Medeiros. “Role of Helicobacter pylori in gastric mucosa-associated lymphoid tissue lymphomas”. World Journal of Gastroenterology, vol. 20, no. 3, pp. 684-698, 2014.

K. E. L. McColl. “Helicobacter pylori infection”. The New England Journal of Medicine, vol. 362, no. 17, pp. 1597-604, 2004.

T. Yucel, D. Aygin, S. Sen and O. Yucel. “The prevalence of Helicobacter pylori and related factors among university students in Turkey”. Japanese Journal of Infectious Diseases, vol. 61, no. 3, pp. 179-183, 2008.

A. A. Hassan, G. M. Elnemr, M. A. Almourgi, A. K. Alzahrani, N. Lilian and O. M. Mehanna. “Study of the effect of hypoxia on the prevalence of Helicobacter pylori infection among Saudi students at Taif university”. Research Journal of Microbiology, vol. 4, pp. 18-24, 2017.

M. A. Al-Madi, A. Aljebreen, F. Tounesi and A. Abdo. “Helicobacter pylori prevalence among medical students in a high endemic area”. Saudi Medical Journal, vol. 28, no. 6, pp. 896-898, 2007.

B. Hussen, S. S. Qader, H. F. Ahmad and S. H. Ahmed. “The prevalence of Helicobacter pylori among university students in Iraq”. Indian Journal of Science and Technology, vol. 6, pp. 4-8, 2013.

J. K. Y. Hooi, W. Y. Lai, W. K. Ng, M. M. Y. Suen, F. E. Underwood, D. Tanyingoh, P. Malfertheiner, D. Y. Graham, V. W. S. Wong, J. C. Y. Wu, F. K. L. Chan, J. J. Y. Sung, G. G. Kaplan and S. C. Ng. “Global prevalence of Helicobacter pylori infection: Systematic review and meta-analysis”. Gastroenterology, vol. 153, no. 2, pp. 420-429, 2017.

S. Agah, H. Khedmat, M. E. Ghamar-Chehred, R. Hadi and A. Aghaei. “Female gender and Helicobacter pylori infection, the most important predisposition factors in a cohort of gastric cancer: A longitudinal study”. Caspian Journal of Internal Medicine, vol. 7, no. 2, pp. 136-141, 2016.

R. M. Nyarango, P. A. Aloo, E. W. Kabiru and B. O. Nyanchongi. “The risk of pathogenic intestinal parasite infections in Kisii municipality, Kenya”. BMC Public Health, vol. 8, pp. 237, 2008.

J. G. Kusters, A. H. M. van Vliet and E. J. Kuipers. “Pathogenesis of Helicobacter pylori infection”. Clinical Microbiology Reviews, vol. 19, no. 3, pp. 449-490, 2006.

M. J. Blaser, Y. Chen and J. Reibmann. “Does Helicobacter pylori protect against asthma and allergy?” Gut, vol. 57, no. 8, pp. 1178-1179, 2008.

J. Michalkiewicz, A. Helmin-Basa, R. Grzywa, M. CzerwionkaSzaflarska, A. Szaflarska-Poplawska, G. Mierzwa, A. Marszalek, M. Bodnar, M. Nowak and K. Dzierzanowska-Fangrat. “Innate immunity components and cytokines in gastric mucosa in children with Helicobacter pylori infection”. Mediators of Inflammation, vol. 10, pp. 1-7, 2015.

M. P. Dore, H. M. Malaty, D. Y. Graham, G. Fanciulli, G. Delitala and G. Realdi. “Risk factors associated with Helicobacter pylori infection among children in a defined geographic area”. Clinical Infectious Diseases, vol. 35, no. 3, pp. 240-245, 2002.

Published
2019-06-30
How to Cite
1.
Maroof S, Alsakee H, Muhammad G, Muhammad A, Rashid I, Sdiq N khan. Prevalence of AntiHelicobacter pylori Antibodies among Students of Cihan University, Erbil. cuesj [Internet]. 30Jun.2019 [cited 18Aug.2022];3(1):66-0. Available from: https://journals.cihanuniversity.edu.iq/index.php/cuesj/article/view/94
Section
Research Article