Retrospective Clinical Evaluation of Platelet-Rich Plasma Application in Oral Surgery in Adults

A Comparative Study with a Control Group

Authors

DOI:

https://doi.org/10.24086/cuesj.v10n1y2026.pp1-5

Keywords:

Platelet-rich plasma, oral surgery procedures, tooth extraction, surgery procedures, tissue healing

Abstract

Platelet-rich plasma (PRP), an autologous blood concentrate rich in platelets and growth factors, has gained popularity in oral surgery due to its potential to enhance healing and reduce post-operative complications. However, its efficacy remains debated due to variations in preparation and application protocols. This retrospective comparative clinical study aimed to evaluate the healing enhancement and safety of PRP in various oral surgical procedures, such as tooth extractions, sinus lifts, periapical surgeries, and cyst enucleations, compared to a control group treated without PRP. A total of 84 adult patients (mean age 42.9 years) were included: 42 received PRP (study group) and 42 underwent standard surgery without PRP (control group). Healing was evaluated clinically and radiographically based on soft tissue closure, post-operative pain (Visual Analog Scale), infection, and bone regeneration. By day 30, complete soft tissue healing was achieved in 94.1% of PRP-treated cases versus 76.4% in controls (P < 0.05). Mean pain score on day 10 was 2.1 in PRP versus 3.8 in control (P < 0.01). Radiographic bone density increased in 6 months by 28.5% in PRP-treated sites and 14.2% in controls (P < 0.01). Patient satisfaction was higher in the PRP group (8.4 vs. 7.1). PRP appears to significantly improve both soft tissue and bone healing in oral surgical procedures compared with standard care, with high patient satisfaction and a favorable safety profile. Further prospective controlled trials are recommended for standardized protocol validation.

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Author Biographies

Ninous P. Philip, Department of Oral and Maxillofacial Surgery, College of Dentistry, Cihan University-Erbil, Kurdistan Region, Iraq

Ninous P. Philip is an assistant professor at  the Department of Oral and Maxillofacial Surgery, College of Dentistry, Cihan University-Erbil, Kurdistan Region, Iraq. He is a member of Iraqi Board For Medical Specializations, Fellowship Degree in oral & Maxillofacial surgery, USA national Board in Dentistry.


Bahoz Himdad, Department of Oral and Maxillofacial Surgery, College of Dentistry, Cihan University-Erbil, Kurdistan Region, Iraq

Bahoz Himdad is a lecturer at the Department of Oral and Maxillofacial Surgery, College of Dentistry, Cihan University-Erbil, Kurdistan Region, Iraq. His research interest is Orthodontics and Dental Surgery.

Amani A. Elfaki, Department of Anatomy, Faculty of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia

Amani A.d Elfaki is the  Head of Basic Medical Sciences Departments, Faculty of Medicine, Al Zaiem Al Azhari University, Khartoum and Head Department of Anatomy, Faculty of Medicine, Al Zaiem Al Azhari University, Khartoum North, SUDAN. Her research interest is Neuroanatomy.

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Published

2026-01-01

How to Cite

1.
Philip NP, Himdad B, Elfaki AA. Retrospective Clinical Evaluation of Platelet-Rich Plasma Application in Oral Surgery in Adults: A Comparative Study with a Control Group. Cihan U Erbil SCI J [Internet]. 2026 Jan. 1 [cited 2026 Jun. 23];10(1):1-5. Available from: https://journals.cihanuniversity.edu.iq/index.php/cuesj/article/view/1590

Issue

Vol. 10 No. 1 (2026)

Section

Research Article

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Copyright (c) 2026 Ninous P. Philip, Bahoz Himdad, Amani A. Elfaki

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