The Essential Pheromonal Elements of the Mouse Preputial Gland in Castrated Treated Mice

Keywords: Testosterone, pheromones, histology, preputial, castration


The present study investigated the 1effects of both castration and manipulation of castrated1 subjects with 0.1 ml of 50µg/kg/day of testosterone at 3 weeks of age for 6 weeks on the pheromonal and histological structure of male mice preputial gland.   The preputial gland results from the control intact group showed that six essential pheromonal compounds are present, whereas the glandular structure revealed well-developed acini with basement membrane and connective tissue around most of them. These findings also showed that castration has deleterious effects on the essential pheromonal compounds which are reduced to two compounds only (the α.-Farnesene and 1- Tetradecanol) as well as the histological sections from such subject appeared many atrophied vacuolated acini. On the other hand, treatment of castrated animals with such dose of testosterone did not show any marked effects on the essential pheromonal compounds but it was able to restore the activities of acinar development as showed by many hypertrophied alveoli.


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Author Biographies

Merza H. Homady, Department of Biomedical Sciences, College of Science, Cihan University-Erbil, Kurdistan Region, Iraq

Merza H. Homady is a Professor at the Department of Biomedical Sciences, College of Science, Cihan University. He got the B.Sc. degree in Biology, the M.Sc. degree in Histology and the Ph.D. degree in Histophysiology and Anatomy. His research interests are in Histophysiology, Pathology, Fertility and Sterility. Dr. Merza is a member of American ISRA Society [International Society for Research on Aggression], American Association for the Advancement of Science (AAAS).

Ali A. Majeed, Department of Pathological Analyses, Faculty of Sciences, Kufa University, Iraq.

Ali Adil Majeed is a Lecturer (Full) with a M.Sc. degree in Functional Histology, and Ph.D. in Cell and Molecular Biology, teaching in the Department of Laboratory Investigations at University of Kufa. I have a B.Sc. degree in General Biology and M.Sc. degree in Functional Histology and and a Ph.D. degree in Cell and Molecular Biology. His research interest includes Genotoxicity, Cell Culture, Cancer Biology.

Maysoon T. Al-Haideri‎, ‎Department of Physiotherapy, Cihan University-Erbil, Kurdistan Region, Iraq

Maysoon T. Al-Haideri. is the  Vice President for Scientific Affairs at Cihan University-Erbil. She has a B.Sc. degree in Pharmacy, M.Sc. degree, M.Phil. Degree, and a Ph.D. degree in Pathology, Also  had a Postdoctoral research fellowship. She is a member of American Society for Biochemistry and Molecular Biology, American Heart Association, Syndicate of Iraqi Pharmacists; Syndicate of Kurdistan Pharmacists. Also, an editor member of Cihan University-Erbil Scientific Journal. Her research interest includes Cardiovascular Diseases, Lipids and Immunology.

Mustafa T. Younis‎, ‎Department of General Biology, Cihan University-Erbil, Kurdistan Region, Iraq

Mustafa Thanoon Younis is an Assistant Lecturer (Full) with a M.Sc. degree in Molecular Biology, teaching in the Department of General Biology at Cihan University-Erbil, Kurdistan Region, F.R. Iraq. He has a B.Sc. degree in General Biology and M.Sc. degree in Molecular Biology. He is a member of Biology Syndicate. His research interest includes Molecular Microbiology, Microbiology, Medical Microbiology.


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How to Cite
Homady M, Majeed A, Al-Haideri‎M, Younis‎M. The Essential Pheromonal Elements of the Mouse Preputial Gland in Castrated Treated Mice. cuesj [Internet]. 20Aug.2022 [cited 1Oct.2022];6(2):36-0. Available from:
Research Article