A Comparison of Chemical Compounds between Anti-Diabetic Drug and Some Medicinal Plants

  • Ali M. Hussein Department of Biomedical Sciences, Cihan University-Erbil, Kurdistan Region, Iraq https://orcid.org/0000-0001-5899-2047
  • Rayan S. Salahalddin Department of Biomedical Sciences, Cihan University-Erbil, Kurdistan Region, Iraq
  • Zhala B. Taha Department of Forestry, College of Agricultural Engineering Science, Salahaddin University, Erbil, Kurdistan Region, Iraq https://orcid.org/0000-0002-2673-4526
  • Hawri A. Majeed Department of Biomedical Sciences, Cihan University-Erbil, Kurdistan Region, Iraq
  • Ali J. Muhialdin Animal Production Department, College of Agricultural Engineering Sciences, University of Garmian, Kalar, ‎Kurdistan Region, Iraq https://orcid.org/0000-0001-8432-4122
  • Rahman K. Faraj Department of Chemistry, College of Science, University of Garmian, Kalar, Kurdistan Region, Iraq https://orcid.org/0000-0003-0905-2846
Keywords: Ocimum basilicum, Trigonella foenum-graecum, Metformin, Chemical Composition, Type 2 diabetes ‎

Abstract

Type 2 diabetes (T2D) is a kind of diabetes marked by high blood sugar, insulin, and insulin insufficiency. Adult-onset diabetes is another name for it. Increased thirst, frequent urination, and unexplained weight loss are common indications and symptoms. Metformin side effects include metallic taste, weakness, diarrhea, stomach upset, lactic acidosis, and vomiting. Two other side effects are asthenia and a Vitamin B12 deficiency. Many recent studies and most health experts recommend basil seed as a better Metformin substitute. The research investigates why patients who consume basil seeds have a similar response to those who take Metformin. The methodology of the study consisted of two main steps, first step is to analyze basil and use HPLC to determine its chemical components. The second step is to compare the broken-down components to Metformin-composed materials, which is done by diluting with methanol/water (50:50 v/v) and removing the fat layer using 20 mL hexane. The findings showed that basil seed and Metformin had the most similar component structure, thus the foundlings concluded that patients had the same responses without the Metformin side effects, implying that basil seed stabilizes blood sugar levels.

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Author Biographies

Ali M. Hussein, Department of Biomedical Sciences, Cihan University-Erbil, Kurdistan Region, Iraq

Ali M. Hussein is a Lecturer at the Department of Biomedical Sciences, College of Science, Cihan University-Erbil. He got the B.Sc. degree in Plant Science, the M.Sc. degree in Bioengineering and the Ph.D. Microbiology. His research interests are in Pathogenic Bacteria, Molecular Microbiology and Biotechnology. Dr. Ali is a member of Microbiology Society journals.

Zhala B. Taha, Department of Forestry, College of Agricultural Engineering Science, Salahaddin University, Erbil, Kurdistan Region, Iraq

Zhala B.Taha is an assistant lecturer at the Department of Forestry, College of Agricultural Engineering Sciences, Salahaddin University. she got the B.Sc. degree in Forestry, the M.Sc. degree in Bioengineering and the Ph.D. bioactive compound. Her research interests are in Active compound, medicinal plants. Dr. Zhala is a member of Forestry Society.

Ali J. Muhialdin, Animal Production Department, College of Agricultural Engineering Sciences, University of Garmian, Kalar, ‎Kurdistan Region, Iraq

Ali J. Muhialdin is Assist. Lecturer at the Department of Animal Science, College of Agricultural Engineering Sciences, University Of Garmian, Kalar, Kurdistan Regional, Iraq. He got the B.Sc. degree in Salahaddin University/ College of Science/ Department of Biology, M.Sc. degree in the Kahramanmaras Sutu Imam University/ Faculty of Medicine, Department of Medical Microbiology. His research interests are in Pathogenic Bacteria, Molecular Microbiology and Biotechnology.

Rahman K. Faraj, Department of Chemistry, College of Science, University of Garmian, Kalar, Kurdistan Region, Iraq

Rahman Karim Faraj is a Lecturer at the Department of Chemistry, College of Science, Garmian University. He got the B.Sc. degree in Biology, the M.Sc. degree and the Ph.D. In Microbiology. His research interests are in Pathogenic Bacteria, Molecular Microbiology and Med lab examination.

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Published
2022-09-20
How to Cite
1.
Hussein A, Salahalddin R, Taha Z, Majeed H, Muhialdin A, Faraj R. A Comparison of Chemical Compounds between Anti-Diabetic Drug and Some Medicinal Plants. cuesj [Internet]. 20Sep.2022 [cited 1Oct.2022];6(2):99-02. Available from: https://journals.cihanuniversity.edu.iq/index.php/cuesj/article/view/705
Section
Research Article